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pi3k akt mtor signaling pathway  (MedChemExpress)


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    MedChemExpress pi3k akt mtor signaling pathway
    Pi3k Akt Mtor Signaling Pathway, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 37 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pi3k akt mtor signaling pathway/product/MedChemExpress
    Average 94 stars, based on 37 article reviews
    pi3k akt mtor signaling pathway - by Bioz Stars, 2026-02
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    Inhibition <t>of</t> <t>CRH-mediated</t> <t>PI3K/AKT/mTOR</t> signaling pathway activation stimulates autophagy and decreases apoptosis. A. Western blot examination of autophagy-related proteins in control (ctrl), CRH-treated and CRH+ast-treated DPCs ( n = 4). B. Western blot examination of apoptosis-related proteins in control, CRH-treated and CRH+rap-treated DPCs ( n = 4). C. TEM images of control (C1), CRH-treated (C2) and CRH+rap-treated (C3) DPCs. Scale bars 500 nm. Nu, nucleus;→, damaged cytomembrane;★, autophagosome;▲, autolysosome. Data are means ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.
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    Inhibition of CRH-mediated PI3K/AKT/mTOR signaling pathway activation stimulates autophagy and decreases apoptosis. A. Western blot examination of autophagy-related proteins in control (ctrl), CRH-treated and CRH+ast-treated DPCs ( n = 4). B. Western blot examination of apoptosis-related proteins in control, CRH-treated and CRH+rap-treated DPCs ( n = 4). C. TEM images of control (C1), CRH-treated (C2) and CRH+rap-treated (C3) DPCs. Scale bars 500 nm. Nu, nucleus;→, damaged cytomembrane;★, autophagosome;▲, autolysosome. Data are means ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.

    Journal: Annals of Medicine

    Article Title: Corticotropin-releasing hormone inhibits autophagy by suppressing PTEN to promote apoptosis in dermal papilla cells

    doi: 10.1080/07853890.2025.2490823

    Figure Lengend Snippet: Inhibition of CRH-mediated PI3K/AKT/mTOR signaling pathway activation stimulates autophagy and decreases apoptosis. A. Western blot examination of autophagy-related proteins in control (ctrl), CRH-treated and CRH+ast-treated DPCs ( n = 4). B. Western blot examination of apoptosis-related proteins in control, CRH-treated and CRH+rap-treated DPCs ( n = 4). C. TEM images of control (C1), CRH-treated (C2) and CRH+rap-treated (C3) DPCs. Scale bars 500 nm. Nu, nucleus;→, damaged cytomembrane;★, autophagosome;▲, autolysosome. Data are means ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.

    Article Snippet: To inhibit the PI3K/AKT/mTOR signalling pathway, DPCs in the CRH group were treated with rapamycin (Rap, MCE, HY-10219, designated as the CRH+Rap group).

    Techniques: Inhibition, Activation Assay, Western Blot, Control